Exosomes Secreted by Apoptosis-Resistant Acute Myeloid Leukemia (AML) Blasts Harbor Regulatory Network Proteins Potentially Involved in Antagonism of Apoptosis

Expression of apoptosis-regulating proteins (B-cell CLL/lymphoma 2 - BCL-2, Myeloid Cell Leukemia 1 - MCL-1, BCL-2 like 1 - BCL-X and BCL-2-associated X protein - BAX) in acute myeloid leukemia (AML) blasts at diagnosis is associated with disease-free survival. We previously found that the initially...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Wojtuszkiewicz, Anna, Schuurhuis, Gerrit J., Kessler, Floortje L., Piersma, Sander R., Knol, Jaco C., Pham, Thang V., Jansen, Gerrit, Musters, René J. P., van Meerloo, Johan, Assaraf, Yehuda G., Kaspers, Gertjan J. L., Zweegman, Sonja, Cloos, Jacqueline, Jimenez, Connie R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2016
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824855/
https://ncbi.nlm.nih.gov/pubmed/26801919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.052944
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