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(Immuno)proteasomes as therapeutic target in acute leukemia

The clinical efficacy of proteasome inhibitors in the treatment of multiple myeloma has encouraged application of proteasome inhibitor containing therapeutic interventions in (pediatric) acute leukemia. Here, we summarize the positioning of bortezomib, as first-generation proteasome inhibitor, and s...

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Bibliografiske detaljer
Udgivet i:Cancer Metastasis Rev
Main Authors: Cloos, Jacqueline, Roeten, Margot SF, Franke, Niels E, van Meerloo, Johan, Zweegman, Sonja, Kaspers, Gertjan JL, Jansen, Gerrit
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5721123/
https://ncbi.nlm.nih.gov/pubmed/29071527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-017-9699-4
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