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Positioning of proteasome inhibitors in therapy of solid malignancies

Targeting of the protein degradation pathway, in particular, the ubiquitin-proteasome system, has emerged as an attractive novel cancer chemotherapeutic modality. Although proteasome inhibitors have been most successfully applied in the treatment of hematological malignancies, they also received con...

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Detalhes bibliográficos
Publicado no:Cancer Chemother Pharmacol
Main Authors: Roeten, Margot S. F., Cloos, Jacqueline, Jansen, Gerrit
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778165/
https://ncbi.nlm.nih.gov/pubmed/29184971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-017-3489-0
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