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Proteasome inhibitors in cancer therapy

The ubiquitin proteasome pathway plays a critical role in regulating many processes in the cell which are important for tumour cell growth and survival. Inhibition of proteasome function has emerged as a powerful strategy for anti-cancer therapy. Clinical validation of the proteasome as a therapeuti...

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Detalhes bibliográficos
Main Authors: Crawford, Lisa J., Walker, Brian, Irvine, Alexandra E.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088792/
https://ncbi.nlm.nih.gov/pubmed/21484190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-011-0121-7
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