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Proteasome inhibitors in cancer therapy
The ubiquitin proteasome pathway plays a critical role in regulating many processes in the cell which are important for tumour cell growth and survival. Inhibition of proteasome function has emerged as a powerful strategy for anti-cancer therapy. Clinical validation of the proteasome as a therapeuti...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer Netherlands
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3088792/ https://ncbi.nlm.nih.gov/pubmed/21484190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-011-0121-7 |
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