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Ubiquitin–proteasome system and the role of its inhibitors in cancer therapy

Despite all the other cells that have the potential to prevent cancer development and metastasis through tumour suppressor proteins, cancer cells can upregulate the ubiquitin–proteasome system (UPS) by which they can degrade tumour suppressor proteins and avoid apoptosis. This system plays an extens...

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Detalhes bibliográficos
Publicado no:Open Biol
Main Authors: Aliabadi, Fatemeh, Sohrabi, Beheshteh, Mostafavi, Ebrahim, Pazoki-Toroudi, Hamidreza, Webster, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080017/
https://ncbi.nlm.nih.gov/pubmed/33906413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.200390
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