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The ubiquitin proteasome system in glia and its role in neurodegenerative diseases
The ubiquitin proteasome system (UPS) is crucial for intracellular protein homeostasis and for degradation of aberrant and damaged proteins. The accumulation of ubiquitinated proteins is a hallmark of many neurodegenerative diseases, including amyotrophic lateral sclerosis, Alzheimer’s, Parkinson’s,...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4126450/ https://ncbi.nlm.nih.gov/pubmed/25152710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2014.00073 |
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