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The ubiquitin proteasome system in glia and its role in neurodegenerative diseases

The ubiquitin proteasome system (UPS) is crucial for intracellular protein homeostasis and for degradation of aberrant and damaged proteins. The accumulation of ubiquitinated proteins is a hallmark of many neurodegenerative diseases, including amyotrophic lateral sclerosis, Alzheimer’s, Parkinson’s,...

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Autors principals: Jansen, Anne H. P., Reits, Eric A. J., Hol, Elly M.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126450/
https://ncbi.nlm.nih.gov/pubmed/25152710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2014.00073
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