Dysregulation of Ubiquitin-Proteasome System in Neurodegenerative Diseases

The ubiquitin-proteasome system (UPS) is one of the major protein degradation pathways, where abnormal UPS function has been observed in cancer and neurological diseases. Many neurodegenerative diseases share a common pathological feature, namely intracellular ubiquitin-positive inclusions formed by...

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Библиографические подробности
Опубликовано в: :Front Aging Neurosci
Главные авторы: Zheng, Qiuyang, Huang, Timothy, Zhang, Lishan, Zhou, Ying, Luo, Hong, Xu, Huaxi, Wang, Xin
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2016
Предметы:
Neuroscience
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5156861/
https://ncbi.nlm.nih.gov/pubmed/28018215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2016.00303
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