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The Retromer Complex and Sorting Nexins in Neurodegenerative Diseases

The retromer complex and associated sorting nexins (SNXs) comprise a critical trafficking machinery which mediates endosomal protein sorting. Retromer and/or SNX dysfunction has been linked to several neurodegenerative diseases including Alzheimer’s disease (AD), Parkinson’s disease (PD), and Down’s...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Zhang, Hongfeng, Huang, Timothy, Hong, Yujuan, Yang, Weijie, Zhang, Xian, Luo, Hong, Xu, Huaxi, Wang, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879135/
https://ncbi.nlm.nih.gov/pubmed/29632483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00079
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