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Ubiquitin–proteasome system and the role of its inhibitors in cancer therapy

Despite all the other cells that have the potential to prevent cancer development and metastasis through tumour suppressor proteins, cancer cells can upregulate the ubiquitin–proteasome system (UPS) by which they can degrade tumour suppressor proteins and avoid apoptosis. This system plays an extens...

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Bibliografiske detaljer
Udgivet i:Open Biol
Main Authors: Aliabadi, Fatemeh, Sohrabi, Beheshteh, Mostafavi, Ebrahim, Pazoki-Toroudi, Hamidreza, Webster, Thomas J.
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080017/
https://ncbi.nlm.nih.gov/pubmed/33906413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.200390
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