Exosomes Secreted by Apoptosis-Resistant Acute Myeloid Leukemia (AML) Blasts Harbor Regulatory Network Proteins Potentially Involved in Antagonism of Apoptosis

Expression of apoptosis-regulating proteins (B-cell CLL/lymphoma 2 - BCL-2, Myeloid Cell Leukemia 1 - MCL-1, BCL-2 like 1 - BCL-X and BCL-2-associated X protein - BAX) in acute myeloid leukemia (AML) blasts at diagnosis is associated with disease-free survival. We previously found that the initially...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Proteomics
Autori principali: Wojtuszkiewicz, Anna, Schuurhuis, Gerrit J., Kessler, Floortje L., Piersma, Sander R., Knol, Jaco C., Pham, Thang V., Jansen, Gerrit, Musters, René J. P., van Meerloo, Johan, Assaraf, Yehuda G., Kaspers, Gertjan J. L., Zweegman, Sonja, Cloos, Jacqueline, Jimenez, Connie R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2016
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824855/
https://ncbi.nlm.nih.gov/pubmed/26801919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.052944
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