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Modulation of RNA Condensation by the DEAD-Box Protein eIF4A

Stress granules are condensates of non-translating mRNAs and proteins involved in the stress response and neurodegenerative diseases. Stress granules form in part through intermolecular RNA-RNA interactions, and to better understand how RNA-based condensation occurs, we demonstrate that RNA is effec...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell
Hauptverfasser: Tauber, Devin, Tauber, Gabriel, Khong, Anthony, Van Treeck, Briana, Pelletier, Jerry, Parker, Roy
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7194247/
https://ncbi.nlm.nih.gov/pubmed/31928844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.12.031
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