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The DEAD-box protein Ded1 modulates translation by the formation and resolution of an eIF4F-mRNA complex

The translation, localization, and degradation of cytoplasmic mRNAs are controlled by the formation and rearrangement of their mRNPs. The conserved Ded1/DDX3 DEAD-box protein functions in an unknown manner to affect both translation initiation and repression. We demonstrate that Ded1 first functions...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hilliker, Angela, Gao, Zhaofeng, Jankowsky, Eckhard, Parker, Roy
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268518/
https://ncbi.nlm.nih.gov/pubmed/21925384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.08.008
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