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Division of labor in an oligomer of the DEAD-box RNA helicase Ded1p
Most aspects of RNA metabolism involve DEAD-box RNA helicases, enzymes that bind and remodel RNA and RNA-protein complexes in an ATP-dependent manner. Here we show that the DEAD-box helicase Ded1p oligomerizes in the cell and in vitro, and unwinds RNA as a trimer. Two protomers bind the single stran...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4546514/ https://ncbi.nlm.nih.gov/pubmed/26212457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.06.030 |
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