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Biochemical differences and similarities between the DEAD-box helicase orthologs DDX3X and Ded1p

DDX3X is a conserved DEAD-box RNA helicase involved in translation initiation and other processes of RNA metabolism. Mutations in human DDX3X and deregulation of its expression are linked to tumorigenesis and intellectual disability. The protein is also targeted by diverse viruses. Previous studies...

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Podrobná bibliografie
Vydáno v:J Mol Biol
Hlavní autoři: Sharma, Deepak, Putnam, Andrea A., Jankowsky, Eckhard
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693625/
https://ncbi.nlm.nih.gov/pubmed/29037760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.10.008
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