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Biochemical differences and similarities between the DEAD-box helicase orthologs DDX3X and Ded1p

DDX3X is a conserved DEAD-box RNA helicase involved in translation initiation and other processes of RNA metabolism. Mutations in human DDX3X and deregulation of its expression are linked to tumorigenesis and intellectual disability. The protein is also targeted by diverse viruses. Previous studies...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Sharma, Deepak, Putnam, Andrea A., Jankowsky, Eckhard
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693625/
https://ncbi.nlm.nih.gov/pubmed/29037760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.10.008
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