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Biochemical differences and similarities between the DEAD-box helicase orthologs DDX3X and Ded1p
DDX3X is a conserved DEAD-box RNA helicase involved in translation initiation and other processes of RNA metabolism. Mutations in human DDX3X and deregulation of its expression are linked to tumorigenesis and intellectual disability. The protein is also targeted by diverse viruses. Previous studies...
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| Udgivet i: | J Mol Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5693625/ https://ncbi.nlm.nih.gov/pubmed/29037760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.10.008 |
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