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Division of labor in an oligomer of the DEAD-box RNA helicase Ded1p

Most aspects of RNA metabolism involve DEAD-box RNA helicases, enzymes that bind and remodel RNA and RNA-protein complexes in an ATP-dependent manner. Here we show that the DEAD-box helicase Ded1p oligomerizes in the cell and in vitro, and unwinds RNA as a trimer. Two protomers bind the single stran...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell
Egile Nagusiak: Putnam, Andrea A., Gao, Zhaofeng, Liu, Fei, Jia, Huijue, Yang, Quansheng, Jankowsky, Eckhard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546514/
https://ncbi.nlm.nih.gov/pubmed/26212457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.06.030
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