Mutational analysis of the DEAD-box RNA helicase eIF4AII characterizes its interaction with transformation suppressor Pdcd4 and eIF4GI

Eukaryotic initiation factor (eIF) 4A unwinds secondary and tertiary structures in the 5′-untranslated region of mRNA, permitting translation initiation. Programmed cell death 4 (Pdcd4) is a novel transformation suppressor and eIF4A-binding partner that inhibits eIF4A helicase activity and translati...

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Hlavní autoři: ZAKOWICZ, HALINA, YANG, HSIN-SHENG, STARK, CRISTI, WLODAWER, ALEXANDER, LARONDE-LEBLANC, NICOLE, COLBURN, NANCY H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Copyright 2005 by RNA Society 2005
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370716/
https://ncbi.nlm.nih.gov/pubmed/15661843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7191905
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