DEAD-box helicase eIF4A2 inhibits CNOT7 deadenylation activity

The CCR4–NOT complex plays an important role in the translational repression and deadenylation of mRNAs. However, little is known about the specific roles of interacting factors. We demonstrate that the DEAD-box helicases eIF4A2 and DDX6 interact directly with the MA3 and MIF domains of CNOT1 and co...

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Publicado en:Nucleic Acids Res
Autores principales: Meijer, Hedda A, Schmidt, Tobias, Gillen, Sarah L, Langlais, Claudia, Jukes-Jones, Rebekah, de Moor, Cornelia H, Cain, Kelvin, Wilczynska, Ania, Bushell, Martin
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2019
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736043/
https://ncbi.nlm.nih.gov/pubmed/31180491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz509
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