DEAD-box helicase eIF4A2 inhibits CNOT7 deadenylation activity

The CCR4–NOT complex plays an important role in the translational repression and deadenylation of mRNAs. However, little is known about the specific roles of interacting factors. We demonstrate that the DEAD-box helicases eIF4A2 and DDX6 interact directly with the MA3 and MIF domains of CNOT1 and co...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Meijer, Hedda A, Schmidt, Tobias, Gillen, Sarah L, Langlais, Claudia, Jukes-Jones, Rebekah, de Moor, Cornelia H, Cain, Kelvin, Wilczynska, Ania, Bushell, Martin
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
RNA and RNA-protein complexes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736043/
https://ncbi.nlm.nih.gov/pubmed/31180491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz509
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