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Modulation of RNA Condensation by the DEAD-Box Protein eIF4A

Stress granules are condensates of non-translating mRNAs and proteins involved in the stress response and neurodegenerative diseases. Stress granules form in part through intermolecular RNA-RNA interactions, and to better understand how RNA-based condensation occurs, we demonstrate that RNA is effec...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Tauber, Devin, Tauber, Gabriel, Khong, Anthony, Van Treeck, Briana, Pelletier, Jerry, Parker, Roy
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7194247/
https://ncbi.nlm.nih.gov/pubmed/31928844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.12.031
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