Deletion of Endonuclease V suppresses chemically induced hepatocellular carcinoma

Endonuclease V (EndoV) is a conserved inosine-specific ribonuclease with unknown biological function. Here, we present the first mouse model lacking EndoV, which is viable without visible abnormalities. We show that endogenous murine EndoV cleaves inosine-containing RNA in vitro, nevertheless a seri...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: Kong, Xiang Yi, Vik, Erik Sebastian, Nawaz, Meh Sameen, Berges, Natalia, Dahl, Tuva Børresdatter, Vågbø, Cathrine, Suganthan, Rajikala, Segers, Filip, Holm, Sverre, Quiles-Jiménez, Ana, Gregersen, Ida, Fladeby, Cathrine, Aukrust, Pål, Bjørås, Magnar, Klungland, Arne, Halvorsen, Bente, Alseth, Ingrun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2020
Konular:
RNA and RNA-protein complexes
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192598/
https://ncbi.nlm.nih.gov/pubmed/32083667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa115
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller