The Human Homolog of Escherichia coli Endonuclease V Is a Nucleolar Protein with Affinity for Branched DNA Structures

Loss of amino groups from adenines in DNA results in the formation of hypoxanthine (Hx) bases with miscoding properties. The primary enzyme in Escherichia coli for DNA repair initiation at deaminated adenine is endonuclease V (endoV), encoded by the nfi gene, which cleaves the second phosphodiester...

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Main Authors: Fladeby, Cathrine, Vik, Erik Sebastian, Laerdahl, Jon K., Gran Neurauter, Christine, Heggelund, Julie E., Thorgaard, Eirik, Strøm-Andersen, Pernille, Bjørås, Magnar, Dalhus, Bjørn, Alseth, Ingrun
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489907/
https://ncbi.nlm.nih.gov/pubmed/23139746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047466
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