AP endonuclease independent repair of abasic sites in Schizosaccharomyces pombe

Abasic (AP) sites are formed spontaneously and are inevitably intermediates during base excision repair of DNA base damages. AP sites are both mutagenic and cytotoxic and key enzymes for their removal are AP endonucleases. However, AP endonuclease independent repair initiated by DNA glycosylases per...

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Bibliographic Details
Main Authors: Nilsen, Line, Forstrøm, Rune J., Bjørås, Magnar, Alseth, Ingrun
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Genome Integrity, Repair and Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3300018/
https://ncbi.nlm.nih.gov/pubmed/22084197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr933
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