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Human AP endonuclease inefficiently removes abasic sites within G4 structures compared to duplex DNA
Excision repair processes are essential to maintain genome stability. A decrease in efficiency and fidelity of these pathways at regions of the genome that can assume non-canonical DNA structures has been proposed as a possible mechanism to explain the increased mutagenesis and consequent diseased s...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4081060/ https://ncbi.nlm.nih.gov/pubmed/24848015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku417 |
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