Identification and characterization of mitochondrial abasic (AP)-endonuclease in mammalian cells

Abasic (AP)-endonuclease (APE) is responsible for repair of AP sites, and single-strand DNA breaks with 3′ blocking groups that are generated either spontaneously or during repair of damaged or abnormal bases via the DNA base excision repair (BER) pathway in both nucleus and mitochondria. Mammalian...

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Bibliographic Details
Main Authors: Chattopadhyay, Ranajoy, Wiederhold, Lee, Szczesny, Bartosz, Boldogh, Istvan, Hazra, Tapas K., Izumi, Tadahide, Mitra, Sankar
Format: Artigo
Language:Inglês
Published: Oxford University Press 2006
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440881/
https://ncbi.nlm.nih.gov/pubmed/16617147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl177
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