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Identification and characterization of mitochondrial abasic (AP)-endonuclease in mammalian cells
Abasic (AP)-endonuclease (APE) is responsible for repair of AP sites, and single-strand DNA breaks with 3′ blocking groups that are generated either spontaneously or during repair of damaged or abnormal bases via the DNA base excision repair (BER) pathway in both nucleus and mitochondria. Mammalian...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1440881/ https://ncbi.nlm.nih.gov/pubmed/16617147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl177 |
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