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Endonuclease V cleaves at inosines in RNA

Endonuclease V orthologues are highly conserved proteins found in all kingdoms of life. While the prokaryotic enzymes are DNA repair proteins for removal of deaminated adenosine (inosine) from the genome, no clear role for the eukaryotic counterparts has hitherto been described. Here we report that...

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Detalhes bibliográficos
Main Authors: Sebastian Vik, Erik, Sameen Nawaz, Meh, Strøm Andersen, Pernille, Fladeby, Cathrine, Bjørås, Magnar, Dalhus, Bjørn, Alseth, Ingrun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741635/
https://ncbi.nlm.nih.gov/pubmed/23912683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3271
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