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Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy

Chondrocyte hypertrophy is an essential process required for endochondral bone formation. Proper regulation of chondrocyte hypertrophy is also required in postnatal cartilage homeostasis. Indian hedgehog (Ihh) and PTHrP signaling play crucial roles in regulating the onset of chondrocyte hypertrophy...

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Bibliographic Details
Published in:Development
Main Authors: Mak, Kinglun Kingston, Kronenberg, Henry M., Chuang, Pao-Tien, Mackem, Susan, Yang, Yingzi
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188307/
https://ncbi.nlm.nih.gov/pubmed/18434416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.018044
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