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PTHrP targets HDAC4 and HDAC5 to repress chondrocyte hypertrophy
During endochondral bone formation, chondrocyte hypertrophy represents a crucial turning point from chondrocyte differentiation to bone formation. Both parathyroid hormone-related protein (PTHrP) and histone deacetylase 4 (HDAC4) inhibit chondrocyte hypertrophy. Using multiple mouse genetics models,...
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| Publicat a: | JCI Insight |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6483522/ https://ncbi.nlm.nih.gov/pubmed/30843886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.97903 |
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