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PTHrP targets Salt-inducible kinases, HDAC4 and HDAC5 to repress chondrocyte hypertrophy in the growth plate
Hypertrophy of chondrocytes is a crucial step in the endochondral bone formation process that drives bone lengthening and the transition to endochondral bone formation. Both Parathyroid hormone-related protein (PTHrP) and Histone deacetylase 4 (HDAC4) inhibit chondrocyte hypertrophy. Use of multiple...
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| Publicado no: | Bone |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7744326/ https://ncbi.nlm.nih.gov/pubmed/33148508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2020.115709 |
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