Indian hedgehog stimulates periarticular chondrocyte differentiation to regulate growth plate length independently of PTHrP

In the developing growth plate, periarticular chondrocytes proliferate, differentiate into columnar chondrocytes, and then further differentiate into postmitotic hypertrophic chondrocytes. Parathyroid hormone–related (PTH-related) protein (PTHrP), regulated by Indian hedgehog (Ihh), prevents prematu...

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Main Authors: Kobayashi, Tatsuya, Soegiarto, Desi W., Yang, Yingzi, Lanske, Beate, Schipani, Ernestina, McMahon, Andrew P., Kronenberg, Henry M.
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2005
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1143590/
https://ncbi.nlm.nih.gov/pubmed/15951842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24397
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