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PTHrP targets Salt-inducible kinases, HDAC4 and HDAC5 to repress chondrocyte hypertrophy in the growth plate

Hypertrophy of chondrocytes is a crucial step in the endochondral bone formation process that drives bone lengthening and the transition to endochondral bone formation. Both Parathyroid hormone-related protein (PTHrP) and Histone deacetylase 4 (HDAC4) inhibit chondrocyte hypertrophy. Use of multiple...

詳細記述

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書誌詳細
出版年:Bone
主要な著者: Nishimori, Shigeki, Wein, Marc N., Kronenberg, Henry M.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744326/
https://ncbi.nlm.nih.gov/pubmed/33148508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2020.115709
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