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Structural biology in antiviral drug discovery

Structural biology has emerged during the last thirty years as a powerful tool for rational drug discovery. Crystal structures of biological targets alone and in complex with ligands and inhibitors provide essential insights into the mechanisms of actions of enzymes, their conformational changes upo...

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Podrobná bibliografie
Vydáno v:Curr Opin Pharmacol
Hlavní autoři: Bassetto, Marcella, Massarotti, Alberto, Coluccia, Antonio, Brancale, Andrea
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Ltd. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185576/
https://ncbi.nlm.nih.gov/pubmed/27611878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2016.08.014
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