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Structural biology in antiviral drug discovery

Structural biology has emerged during the last thirty years as a powerful tool for rational drug discovery. Crystal structures of biological targets alone and in complex with ligands and inhibitors provide essential insights into the mechanisms of actions of enzymes, their conformational changes upo...

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Bibliografiske detaljer
Udgivet i:Curr Opin Pharmacol
Main Authors: Bassetto, Marcella, Massarotti, Alberto, Coluccia, Antonio, Brancale, Andrea
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Ltd. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185576/
https://ncbi.nlm.nih.gov/pubmed/27611878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2016.08.014
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