High-Throughput Screening Normalized To Biological Response: Application To Antiviral Drug Discovery

The process of conducting cell-based phenotypic screens can result in datasets from small libraries or portions of large libraries, making accurate hit picking from multiple datasets important for efficient drug discovery. Here, we describe a screen design and data analysis approach that allows for...

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Hauptverfasser: Patel, Dhara A., Patel, Anand C., Nolan, William C., Huang, Guangming, Romero, Arthur G., Charlton, Nichole, Agapov, Eugene, Zhang, Yong, Holtzman, Michael J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867592/
https://ncbi.nlm.nih.gov/pubmed/23860224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057113496848
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