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High Throughput Screening for Small Molecule Enhancers of the Interferon Signaling Pathway to Drive Next-Generation Antiviral Drug Discovery

Most of current strategies for antiviral therapeutics target the virus specifically and directly, but an alternative approach to drug discovery might be to enhance the immune response to a broad range of viruses. Based on clinical observation in humans and successful genetic strategies in experiment...

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Détails bibliographiques
Auteurs principaux: Patel, Dhara A., Patel, Anand C., Nolan, William C., Zhang, Yong, Holtzman, Michael J.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344904/
https://ncbi.nlm.nih.gov/pubmed/22574190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036594
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