Discovery of small molecule inhibitors of xyloglucan endotransglucosylase (XET) activity by high-throughput screening

Small molecules (xenobiotics) that inhibit cell-wall-localised enzymes are valuable for elucidating the enzymes’ biological roles. We applied a high-throughput fluorescent dot-blot screen to search for inhibitors of Petroselinum xyloglucan endotransglucosylase (XET) activity in vitro. Of 4216 xenobi...

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Vydáno v:Phytochemistry
Hlavní autoři: Chormova, Dimitra, Franková, Lenka, Defries, Andrew, Cutler, Sean R., Fry, Stephen C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560162/
https://ncbi.nlm.nih.gov/pubmed/26093490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phytochem.2015.06.016
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