A carregar...
Discovery of Small Molecule Inhibitors of Human Uridine-Cytidine Kinase 2 by High-Throughput Screening
Clinically relevant inhibitors of dihydroorotate dehydrogenase (DHODH), a rate-limiting enzyme in mammalian de novo pyrimidine synthesis, have strong antiviral and anticancer activity in vitro. However, they are ineffective in vivo due to efficient uridine salvage by infected or rapidly dividing cel...
Na minha lista:
| Publicado no: | Bioorg Med Chem Lett |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6719797/ https://ncbi.nlm.nih.gov/pubmed/31420268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2019.08.010 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|