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Structural biology in antiviral drug discovery

Structural biology has emerged during the last thirty years as a powerful tool for rational drug discovery. Crystal structures of biological targets alone and in complex with ligands and inhibitors provide essential insights into the mechanisms of actions of enzymes, their conformational changes upo...

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Detalhes bibliográficos
Publicado no:Curr Opin Pharmacol
Main Authors: Bassetto, Marcella, Massarotti, Alberto, Coluccia, Antonio, Brancale, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185576/
https://ncbi.nlm.nih.gov/pubmed/27611878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2016.08.014
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