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Structural biology in antiviral drug discovery

Structural biology has emerged during the last thirty years as a powerful tool for rational drug discovery. Crystal structures of biological targets alone and in complex with ligands and inhibitors provide essential insights into the mechanisms of actions of enzymes, their conformational changes upo...

Полное описание

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Библиографические подробности
Опубликовано в: :Curr Opin Pharmacol
Главные авторы: Bassetto, Marcella, Massarotti, Alberto, Coluccia, Antonio, Brancale, Andrea
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier Ltd. 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185576/
https://ncbi.nlm.nih.gov/pubmed/27611878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2016.08.014
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