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Structural biology in antiviral drug discovery

Structural biology has emerged during the last thirty years as a powerful tool for rational drug discovery. Crystal structures of biological targets alone and in complex with ligands and inhibitors provide essential insights into the mechanisms of actions of enzymes, their conformational changes upo...

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Publicat a:Curr Opin Pharmacol
Autors principals: Bassetto, Marcella, Massarotti, Alberto, Coluccia, Antonio, Brancale, Andrea
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Ltd. 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185576/
https://ncbi.nlm.nih.gov/pubmed/27611878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2016.08.014
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