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Elevated p38MAPK activity promotes neural stem cell aging
Age-progressive neural stem cell (NSC) dysfunction leads to impaired neurogenesis, cognitive decline and the onset of age-related neurodegenerative pathologies. p38MAPK signalling pathway limits stem cell activity during aging in several tissues. Its role in NSCs remains controversial. In this work,...
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| 發表在: | Aging (Albany NY) |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Impact Journals
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7185101/ https://ncbi.nlm.nih.gov/pubmed/32243258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102994 |
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