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SOX2 haploinsufficiency promotes impaired vision at advanced age
Age-related vision loss has been associated with degeneration of the retina and decline in Müller glia cell activity. Sox2 is a critical transcription factor for the development and maintenance of the mammalian retina. Here we determined the role of Sox2 in retinal aging. We observed a decline in th...
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| 發表在: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Impact Journals LLC
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6291181/ https://ncbi.nlm.nih.gov/pubmed/30613351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26393 |
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