Elevated p38MAPK activity promotes neural stem cell aging

Age-progressive neural stem cell (NSC) dysfunction leads to impaired neurogenesis, cognitive decline and the onset of age-related neurodegenerative pathologies. p38MAPK signalling pathway limits stem cell activity during aging in several tissues. Its role in NSCs remains controversial. In this work,...

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Bibliografiske detaljer
Udgivet i:Aging (Albany NY)
Main Authors: Moreno-Cugnon, Leire, Arrizabalaga, Olatz, Llarena, Irantzu, Matheu, Ander
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185101/
https://ncbi.nlm.nih.gov/pubmed/32243258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102994
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