COX-2/sEH dual inhibitor PTUPB alleviates bleomycin-induced pulmonary fibrosis in mice via inhibiting senescence

Pulmonary fibrosis (PF) is a senescence-associated disease with poor prognosis. Currently, there is no effective therapeutic strategy for preventing and treating the disease process. Mounting evidence suggests that arachidonic acid (ARA) metabolites are involved in the pathogenesis of various fibros...

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Pubblicato in:FEBS J
Autori principali: Zhang, Chen-Yu, Duan, Jia-Xi, Yang, Hui-Hui, Sun, Chen-Chen, Zhong, Wen-Jing, Tao, Jia-Hao, Guan, Xin-Xin, Jiang, Hui-Ling, Hammock, Bruce D., Hwang, Sung Hee, Zhou, Yong, Guan, Cha-Xiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174142/
https://ncbi.nlm.nih.gov/pubmed/31646730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.15105
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