Effect Of Dual sEH/COX-2 Inhibition on Allergen-Induced Airway Inflammation

Arachidonic acid metabolites resulting from the cyclooxygenase (COX), lipoxygenase, and cytochrome P450 oxidase enzymatic pathways play pro- and anti-inflammatory roles in allergic airway inflammation (AAI) and asthma. Expression of COX-2 and soluble epoxide hydrolase (sEH) are elevated in allergic...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Dileepan, Mythili, Rastle-Simpson, Stephanie, Greenberg, Yana, Wijesinghe, Dayanjan S., Kumar, Naren Gajenthra, Yang, Jun, Hwang, Sung Hee, Hammock, Bruce D., Sriramarao, P., Rao, Savita P.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777353/
https://ncbi.nlm.nih.gov/pubmed/31611798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01118
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