COX-2/sEH dual inhibitor PTUPB alleviates bleomycin-induced pulmonary fibrosis in mice via inhibiting senescence

Pulmonary fibrosis (PF) is a senescence-associated disease with poor prognosis. Currently, there is no effective therapeutic strategy for preventing and treating the disease process. Mounting evidence suggests that arachidonic acid (ARA) metabolites are involved in the pathogenesis of various fibros...

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Bibliographic Details
Published in:FEBS J
Main Authors: Zhang, Chen-Yu, Duan, Jia-Xi, Yang, Hui-Hui, Sun, Chen-Chen, Zhong, Wen-Jing, Tao, Jia-Hao, Guan, Xin-Xin, Jiang, Hui-Ling, Hammock, Bruce D., Hwang, Sung Hee, Zhou, Yong, Guan, Cha-Xiang
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174142/
https://ncbi.nlm.nih.gov/pubmed/31646730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.15105
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