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Aberrant Glycosylation of the IgA1 molecule in IgA Nephropathy

IgA nephropathy, the most common primary glomerulonephritis in the world and a frequent cause of end-stage renal disease, is characterized by typical mesangial deposits of IgA1, as first described by Berger and Hinglais in 1968. Since then, it was discovered that aberrant IgA1 O-glycosylation is inv...

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Bibliographic Details
Published in:Semin Nephrol
Main Authors: Novak, Jan, Barratt, Jonathan, Julian, Bruce A., Renfrow, Matthew B.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7170174/
https://ncbi.nlm.nih.gov/pubmed/30177018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semnephrol.2018.05.016
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