Role of Aberrant Glycosylation of IgA1 Molecules in the Pathogenesis of IgA Nephropathy

Studies of the properties of immune complexes (IC) in the circulation, urine, and mesangium of IgA nephropathy (IgAN) patients have provided data relevant to the pathogenesis of this disease. IC contain predominantly polymeric IgA1 molecules which are deficient in galactose (Gal) residues on O-linke...

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Autores principales: Mestecky, J., Tomana, M., Moldoveanu, Z., Julian, B.A., Suzuki, H., Matousovic, K., Renfrow, M.B., Novak, L., Wyatt, R.J., Novak, J.
Formato: Artigo
Lenguaje:Inglês
Publicado: S. Karger AG 2008
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821435/
https://ncbi.nlm.nih.gov/pubmed/18182777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000112922
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