Aberrant Glycosylation of IgA1 is Inherited in Pediatric IgA Nephropathy and Henoch-Schönlein Purpura Nephritis

Serum galactose-deficient IgA1 (Gd-IgA1) is an inherited risk factor for adult IgA nephropathy (IgAN). The goal of this study is to determine the heritability of serum Gd-IgA1 levels in children with IgAN and Henoch-Schönlein nephritis (HSPN). For this purpose, we obtained serum from 34 Caucasian fa...

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Hauptverfasser: Kiryluk, Krzysztof, Moldoveanu, Zina, Sanders, John T., Eison, T. Matthew, Suzuki, Hitoshi, Julian, Bruce A., Novak, Jan, Gharavi, Ali G., Wyatt, Robert J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641561/
https://ncbi.nlm.nih.gov/pubmed/21326171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2011.16
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