Differential expression of MAGEA6 toggles autophagy to promote pancreatic cancer progression

The melanoma-associated antigen family A (MAGEA) antigens are expressed in a wide variety of malignant tumors but not in adult somatic cells, rendering them attractive targets for cancer immunotherapy. Here we show that a number of cancer-associated MAGEA mutants that undergo proteasome-dependent de...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Tsang, Yiu Huen, Wang, Yumeng, Kong, Kathleen, Grzeskowiak, Caitlin, Zagorodna, Oksana, Dogruluk, Turgut, Lu, Hengyu, Villafane, Nicole, Bhavana, Venkata Hemanjani, Moreno, Daniela, Elsea, Sarah H, Liang, Han, Mills, Gordon B, Scott, Kenneth L
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164953/
https://ncbi.nlm.nih.gov/pubmed/32270762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48963
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