Differential expression of MAGEA6 toggles autophagy to promote pancreatic cancer progression

The melanoma-associated antigen family A (MAGEA) antigens are expressed in a wide variety of malignant tumors but not in adult somatic cells, rendering them attractive targets for cancer immunotherapy. Here we show that a number of cancer-associated MAGEA mutants that undergo proteasome-dependent de...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Tsang, Yiu Huen, Wang, Yumeng, Kong, Kathleen, Grzeskowiak, Caitlin, Zagorodna, Oksana, Dogruluk, Turgut, Lu, Hengyu, Villafane, Nicole, Bhavana, Venkata Hemanjani, Moreno, Daniela, Elsea, Sarah H, Liang, Han, Mills, Gordon B, Scott, Kenneth L
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2020
Matèries:
Cancer Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164953/
https://ncbi.nlm.nih.gov/pubmed/32270762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48963
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