Differential expression of MAGEA6 toggles autophagy to promote pancreatic cancer progression

The melanoma-associated antigen family A (MAGEA) antigens are expressed in a wide variety of malignant tumors but not in adult somatic cells, rendering them attractive targets for cancer immunotherapy. Here we show that a number of cancer-associated MAGEA mutants that undergo proteasome-dependent de...

Full description

Saved in:
Bibliographic Details
Published in:eLife
Main Authors: Tsang, Yiu Huen, Wang, Yumeng, Kong, Kathleen, Grzeskowiak, Caitlin, Zagorodna, Oksana, Dogruluk, Turgut, Lu, Hengyu, Villafane, Nicole, Bhavana, Venkata Hemanjani, Moreno, Daniela, Elsea, Sarah H, Liang, Han, Mills, Gordon B, Scott, Kenneth L
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2020
Subjects:
Cancer Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164953/
https://ncbi.nlm.nih.gov/pubmed/32270762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48963
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items