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Oncogenic MAGEA-TRIM28 ubiquitin ligase downregulates autophagy by ubiquitinating and degrading AMPK in cancer

Autophagy is commonly altered in cancer and has a complicated, but important role in regulation of tumor growth. Autophagy is often tumor suppressive in the early stages of cancer development, but contributes to the late stages of tumor growth. Because of this, putative oncogenes that modulate autop...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Autophagy
Prif Awduron: Pineda, Carlos T, Potts, Patrick Ryan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509443/
https://ncbi.nlm.nih.gov/pubmed/25945414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1034420
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